Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242301 | 0.88 | KMT2A (0.38) | FDPSKMT2AHCAR3HCAR2PPARG | |
| SCHEMBL6244718 | 0.83 | FDPS (0.53) | FDPSFDFT1KMT2APPARGPPARA | |
| SCHEMBL6239582 | 0.80 | FDPS (0.50) | FDPSFDFT1KMT2APPARGPPARA | |
| SCHEMBL19642981 | 0.70 | PPARG (0.49) | KMT2APPARGPPARALMNACYP2D6 | |
| SCHEMBL6244360 | 0.69 | PPARG (0.36) | FDPSKMT2APPARGPPARAMEN1 | |
| SCHEMBL5156538 | 0.69 | FDPS (1.00) | FDPSFDFT1LMNA | |
| SCHEMBL6243007 | 0.68 | MAPT (0.45) | KMT2APPARGPPARAMEN1GMNN | |
| SCHEMBL6241825 | 0.67 | PPARG (0.40) | FDPSFDFT1PPARGPPARAMAPT | |
| SCHEMBL4782822 | 0.67 | CYP2D6 (0.47) | KMT2APPARGPPARALMNACYP2D6 | |
| SCHEMBL19468562 | 0.66 | FDPS (0.51) | FDPSKMT2APPARGPPARACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028488-A1 | HETEROARYL PHOSPHINYL AND THIOPHOSPHINYL COMPOUNDS FOR REGULATION OF GLUCOSE, TRIGLYCERIDES, AND LDL/HDL LEVELS | QUATRX PHARMACEUTICALS CO. (US) | 2005-03-31 | — | — | WO | claimed |