Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243007 | 0.87 | MAPT (0.45) | KMT2APPARGMAPTALDH1A1KDM4E | |
| SCHEMBL6244718 | 0.84 | FDPS (0.53) | FDPSKMT2APPARGCYP2C19CYP2D6 | |
| SCHEMBL6258415 | 0.80 | FDPS (0.49) | FDPSKMT2APPARGMAPTMEN1 | |
| SCHEMBL5668267 | 0.75 | KMT2A (0.53) | KMT2APPARGMAPTALDH1A1KDM4E | |
| SCHEMBL20377227 | 0.74 | FDPS (0.51) | FDPSPPARGTSHRPPARAFDFT1 | |
| SCHEMBL7784532 | 0.73 | FDPS (0.52) | FDPSKMT2AMEN1CYP2C19LMNA | |
| SCHEMBL6244360 | 0.72 | PPARG (0.36) | FDPSKMT2APPARGMAPTALDH1A1 | |
| SCHEMBL7793628 | 0.71 | FDPS (0.60) | FDPSALDH1A1LMNAFDFT1 | |
| SCHEMBL6242301 | 0.71 | KMT2A (0.38) | FDPSKMT2APPARGMAPTALDH1A1 | |
| SCHEMBL7920967 | 0.70 | KMT2A (0.60) | KMT2APPARGMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028488-A1 | HETEROARYL PHOSPHINYL AND THIOPHOSPHINYL COMPOUNDS FOR REGULATION OF GLUCOSE, TRIGLYCERIDES, AND LDL/HDL LEVELS | QUATRX PHARMACEUTICALS CO. (US) | 2005-03-31 | — | — | WO | claimed |
| WO-2005028488-A1 | HETEROARYL PHOSPHINYL AND THIOPHOSPHINYL COMPOUNDS FOR REGULATION OF GLUCOSE, TRIGLYCERIDES, AND LDL/HDL LEVELS | QUATRX PHARMACEUTICALS CO. (US) | 2005-03-31 | — | — | WO | disclosed |