Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263873 | 0.98 | CA12 (0.34) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6257802 | 0.90 | LPAR3 (0.37) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6260633 | 0.89 | LPAR3 (0.40) | LPAR3LPAR2LPAR1S1PR4S1PR1 | |
| SCHEMBL15529174 | 0.77 | LPAR3 (0.43) | LPAR3LPAR2LPAR1FBP1 | |
| SCHEMBL6261401 | 0.74 | LPAR3 (0.32) | LPAR3LPAR2LPAR1 | |
| SCHEMBL6260712 | 0.73 | S1PR4 (0.30) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6257820 | 0.72 | CA12 (0.34) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6261977 | 0.71 | MMP2 (0.36) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6260667 | 0.70 | METAP1 (0.33) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL15373690 | 0.70 | CNR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |