Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261906 | 0.74 | PIN1 (0.41) | — | |
| SCHEMBL6261064 | 0.74 | EPHX2 (0.39) | — | |
| SCHEMBL6258650 | 0.73 | CA12 (0.32) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6263873 | 0.72 | CA12 (0.34) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6262020 | 0.72 | — | — | |
| SCHEMBL6258485 | 0.72 | PIN1 (0.51) | — | |
| SCHEMBL6257802 | 0.71 | LPAR3 (0.37) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6260667 | 0.71 | METAP1 (0.33) | — | |
| SCHEMBL6260633 | 0.70 | LPAR3 (0.40) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6261704 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |