Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269798 | 0.79 | ALDH1A1 (0.52) | POLBSMN1; SMN2THRBHTTCHRM4 | |
| SCHEMBL4182437 | 0.77 | MMP13 (0.61) | MMP13POLBSMN1; SMN2THRBSLC22A8 | |
| SCHEMBL8358839 | 0.76 | MMP13 (0.71) | MMP13POLBSMN1; SMN2THRBLMNA | |
| SCHEMBL12472899 | 0.74 | ALDH1A1 (0.59) | POLBSMN1; SMN2THRBHTTLMNA | |
| SCHEMBL27106875 | 0.73 | MEN1 (0.56) | SMN1; SMN2THRBHTTLMNATP53 | |
| SCHEMBL7897358 | 0.73 | GRM5 (0.70) | — | |
| SCHEMBL6257633 | 0.73 | KMT2A (0.56) | POLBSMN1; SMN2THRBHTTCHRM4 | |
| SCHEMBL4173194 | 0.73 | MMP13 (0.78) | MMP13SLC22A8 | |
| SCHEMBL244641 | 0.72 | SCD (0.58) | SMN1; SMN2HTTCHRM4LMNATP53 | |
| SCHEMBL8357428 | 0.72 | MMP13 (0.90) | MMP13POLBSMN1; SMN2THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070889-A1 | HERBICIDAL AMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |