Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258847 | 0.93 | KMT2A (0.36) | THRATHRBTP53RXRAPPARG | |
| SCHEMBL6252173 | 0.85 | TSHR (0.42) | THRBSMN1; SMN2 | |
| SCHEMBL5587448 | 0.81 | THRA (0.38) | THRATHRBTP53ESR1RXRA | |
| SCHEMBL5588020 | 0.81 | THRA (0.43) | THRATHRBESR1SMPD1 | |
| SCHEMBL6259480 | 0.80 | ESR1 (0.40) | THRATHRBSLC6A5ESR1SMPD1 | |
| SCHEMBL6233139 | 0.80 | ALOX5 (0.41) | THRATHRBTP53ESR1PPARG | |
| SCHEMBL6233436 | 0.80 | CYSLTR2 (0.42) | THRATHRBPPARG | |
| SCHEMBL5589982 | 0.80 | THRA (0.45) | THRATHRBESR1SMPD1 | |
| SCHEMBL5590501 | 0.80 | THRA (0.45) | THRATHRBESR1SMPD1 | |
| SCHEMBL5589143 | 0.80 | THRA (0.45) | THRATHRBESR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |