Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388021 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3F10 | |
| SCHEMBL16361760 | 0.78 | CYP3A4 (0.43) | GAAMEN1KMT2AF10ALDH1A1 | |
| SCHEMBL15076123 | 0.77 | POLB (0.46) | ALDH1A1NR1I2OPRK1CHRNA4KCNH2 | |
| Hydrochloric Acid SCHEMBL15058462 | 0.76 | POLB (0.44) | F10ALDH1A1NR1I2OPRK1CHRNA4 | |
| SCHEMBL5395497 | 0.75 | F10 (0.43) | GAAKDM4EF10HRH3MAPT | |
| SCHEMBL6258693 | 0.74 | CYP3A4 (0.47) | GAAKDM4EADRA2CMEN1KMT2A | |
| SCHEMBL6258733 | 0.74 | MAPT (0.40) | KDM4EADRA2CMEN1KMT2AF10 | |
| SCHEMBL6260533 | 0.73 | GAA (0.47) | GAAKDM4EADRA2CMEN1KMT2A | |
| SCHEMBL1028976 | 0.71 | F10 (0.45) | F10F2 | |
| SCHEMBL9734935 | 0.71 | CXCR4 (0.43) | GAAKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307431-B1 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-10-26 | — | — | EP | disclosed |
| US-6541639-B2 | Condensation reaction of 2-fluoro-4-iodoaniline with 2-(N,N-dimethylamino) in presence of 8-hydroxyquinoline and copper iodide | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20020099225-A1 | Efficient ligand-mediated ullmann coupling of anilnies and azoles | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099225-A1 | Efficient ligand-mediated ullmann coupling of anilnies and azoles | F12, F2, UTS2R | GAA 3327/4885KDM4E 749/4885ADRA2C 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.