Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428964 | 0.81 | CYP3A4 (0.50) | CYP3A4CYP2E1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL6260533 | 0.81 | GAA (0.47) | CYP3A4GAAKDM4EMEN1KMT2A | |
| SCHEMBL15778631 | 0.79 | CYP3A4 (0.53) | CYP3A4CYP2E1CYP2A6KDM4EMEN1 | |
| SCHEMBL11764095 | 0.79 | GAA (0.41) | GAAKDM4EMEN1KMT2AUSP2 | |
| SCHEMBL19029697 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2E1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL28144636 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2E1CYP2A6GAAKDM4E | |
| SCHEMBL12342913 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2E1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL113850 | 0.77 | CYP3A4 (0.44) | CYP3A4CYP2E1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL15445107 | 0.76 | CYP3A4 (0.46) | CYP3A4CYP2E1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL9405397 | 0.75 | NPC1 (0.49) | CYP3A4CYP2E1CYP2A6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327411-A1 | SIRT6 ACTIVATORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-10-03 | — | — | US | disclosed |
| US-11993729-B2 | Chemical mechanical polishing composition | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| EP-3714012-B1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2023-01-11 | — | — | EP | disclosed |
| US-20210102093-A1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2021-04-08 | — | — | US | disclosed |
| US-10899945-B2 | Use of a chemical mechanical polishing (CMP) composition for polishing of cobalt comprising substrates | BASF SE (DE) | 2021-01-26 | — | — | US | disclosed |
| EP-3714012-A1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2020-09-30 | — | — | EP | disclosed |
| US-20200299547-A1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2020-09-24 | — | — | US | disclosed |
| EP-3334794-B1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2019101555-A1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2019-05-31 | — | — | WO | disclosed |
| EP-3334794-A1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1307431-B1 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1307431-A2 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | disclosed |
| US-6541639-B2 | Condensation reaction of 2-fluoro-4-iodoaniline with 2-(N,N-dimethylamino) in presence of 8-hydroxyquinoline and copper iodide | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20020099225-A1 | Efficient ligand-mediated ullmann coupling of anilnies and azoles | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-25 | — | — | US | disclosed |
| WO-2002008199-A2 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| EP-0354224-A1 | NITROGEN-CONTAINING ESTERS OF CARBOXY-CONTAINING INTERPOLYMERS | The Lubrizol Corporation (US) | 1990-02-14 | — | — | EP | disclosed |
| US-4602031-A | Anti-depressant imidazoles, compositions and use | EISAI CO., LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| US-4533669-A | NONTOXIC | EISAI CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4402966-A | Acylaminophenyl imidazoles and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1983-09-06 | — | — | US | disclosed |
| US-4301169-A | Novel imidazole compound and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327411-A1 | SIRT6 ACTIVATORS | SIRT6, SIRT1, SIRT2 | CYP3A4 4281/4885CYP2E1 4094/4885CYP2A6 727/4885 |
| US-20020099225-A1 | Efficient ligand-mediated ullmann coupling of anilnies and azoles | F12, F2, UTS2R | CYP3A4 61/4885CYP2E1 1256/4885CYP2A6 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.