Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279344 | 0.79 | THRB (0.48) | ALDH1A1L3MBTL1LMNATHRBMEN1 | |
| SCHEMBL30660164 | 0.69 | AURKA (0.48) | CXCR4ALDH1A1L3MBTL1LMNATHRB | |
| SCHEMBL2338990 | 0.69 | CYP2A13 (0.64) | CXCR4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6260533 | 0.68 | GAA (0.47) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9423982 | 0.67 | CYP2A13 (0.62) | CXCR4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1054071 | 0.67 | CXCR4 (0.66) | CXCR4ALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL31426439 | 0.67 | CXCR4 (0.66) | CXCR4ALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL127620 | 0.66 | KEAP1 (0.64) | ALDH1A1L3MBTL1LMNATHRBMEN1 | |
| SCHEMBL30443433 | 0.66 | KEAP1 (0.64) | ALDH1A1L3MBTL1LMNATHRBMEN1 | |
| SCHEMBL6258693 | 0.66 | CYP3A4 (0.47) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166344-A | Process for the preparation of imidazoquinoxalinones | BERLEX LABORATORIES, INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5055465-A | IMIDAZOQUINOXALINONES, THEIR AZA ANALOGS AND PROCESS FOR THEIR PREPARATION | BERLEX LABORATORIES, INC. (US) | 1991-10-08 | — | — | US | disclosed |