Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.53 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942520 | 0.86 | ELANE (0.61) | ELANECTSKKLK1PRTN3ATM | |
| SCHEMBL1239037 | 0.85 | KYNU (0.55) | ELANEKLK1PRTN3ATMTP53 | |
| SCHEMBL26854257 | 0.85 | KYNU (0.55) | ELANEKLK1PRTN3ATMTP53 | |
| SCHEMBL15549899 | 0.85 | ELANE (0.54) | ELANEKLK1PRTN3HSD17B10ATM | |
| SCHEMBL14376753 | 0.84 | F2 (0.63) | ELANEACE2 | |
| SCHEMBL5689257 | 0.84 | ELANE (0.77) | ELANEKLK1PRTN3TP53 | |
| SCHEMBL10954084 | 0.83 | ELANE (0.55) | ELANECTSKPRTN3ATMACE2 | |
| SCHEMBL8740045 | 0.83 | ELANE (0.60) | ELANECTSKPRTN3ATMACE2 | |
| SCHEMBL4163321 | 0.83 | ELANE (0.60) | ELANECTSKPRTN3ATMACE2 | |
| SCHEMBL11567174 | 0.83 | ELANE (0.60) | ELANECTSKPRTN3ATMACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005067939-A1 | THERAPEUTICALLY USEFUL ANTIBACTERIAL COMPOUNDS | OXOID LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |