Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 18/20 | 0.82 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.69 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.65 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247109 | 0.89 | CHEK2 (0.70) | CHEK2NR4A2PKN1PKN2 | |
| SCHEMBL20982670 | 0.87 | CHEK2 (0.86) | CHEK2PKN1PKN2 | |
| SCHEMBL27528263 | 0.84 | MEN1 (0.74) | CHEK2PKN1PKN2 | |
| Terephthalamide SCHEMBL28143925 | 0.83 | CHEK2 (0.75) | CHEK2PKN1PKN2 | |
| SCHEMBL6260767 | 0.83 | MMP2 (0.78) | CHEK2PKN1PKN2 | |
| SCHEMBL3922046 | 0.82 | CHEK2 (0.81) | CHEK2NR4A2PKN1PKN2 | |
| SCHEMBL30938560 | 0.82 | NR4A2 (1.00) | CHEK2NR4A2 | |
| SCHEMBL24312910 | 0.81 | PLAU (0.71) | CHEK2PKN1PKN2 | |
| SCHEMBL29557707 | 0.81 | PLAU (0.71) | CHEK2PKN1PKN2 | |
| SCHEMBL6259639 | 0.81 | SMN1; SMN2 (0.76) | CHEK2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |