Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30166038 | 1.00 | FDPS (0.55) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| Water SCHEMBL27592739 | 0.98 | FDPS (0.54) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL8464130 | 0.87 | FDPS (0.50) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL9936014 | 0.85 | FDPS (0.62) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL364678 | 0.82 | FDPS (0.56) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL4020843 | 0.82 | FDPS (0.51) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL3671306 | 0.82 | FDPS (0.51) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL31024294 | 0.82 | FDPS (0.51) | FDPSADORA2AADORA1LTA4HHDAC1 | |
| SCHEMBL9597540 | 0.82 | FDPS (0.55) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL5017277 | 0.82 | FDPS (0.51) | FDPSADORA2AADORA1LTA4HHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101544641-A | Novel anticancer-active purine nucleoside compounds modified by monoazacrown ether at 6-position and preparation method thereof | UNIV HENAN NORMAL | 2009-09-30 | — | — | CN | claimed |
| WO-2023086970-A2 | METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACIDS AND NUCLEASES IN A BODY FLUID AS INDICATORS OF DISEASE | ARNA GENOMICS US INCORPORATED (US) | 2023-05-19 | — | — | WO | disclosed |
| CN-115677807-A | 6-position alpha-hydroxyalkylated purine compounds and methods for modification thereof | 鲁东大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115583950-A | Method for modifying purine Compounds and 6-position acylpurine Compounds | 鲁东大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-101544641-B | Novel anticancer-active purine nucleoside compounds modified by monoazacrown ether at 6-position and preparation method thereof | UNIV HENAN NORMAL | 2010-12-08 | — | — | CN | disclosed |
| CN-101544641-A | Novel anticancer-active purine nucleoside compounds modified by monoazacrown ether at 6-position and preparation method thereof | UNIV HENAN NORMAL | 2009-09-30 | — | — | CN | disclosed |
| CN-101492449-A | 6-N,N-dihydroxyethyl purine new compounds with anticancer activity and preparation method thereof | UNIV HENAN NORMAL (CN) | 2009-07-29 | — | — | CN | disclosed |
| CN-100455583-C | 2-amino-9- (2-substituted ethyl) purines and methods of using same to prepare 9- [ 4-acetoxy-3- (acetoxymethyl) butan-1-yl ] -2-aminopurine | KYUNGDONG PHARM CO LTD (KR) | 2009-01-28 | — | — | CN | disclosed |
| CN-1791602-A | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9- 4-acetoxy-3-(acetoxymethyl)but-1-yl]- 2- aminopurine using the same | KYUNGDONG PHARM CO LTD (KR) | 2006-06-21 | — | — | CN | disclosed |
| CN-1234718-C | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-01-04 | — | — | CN | disclosed |
| WO-2005065668-A2 | TOPICAL COMPOSITIONS COMPRISING HALO-DEOXYADENOSINES FOR TREATMENT OF SKIN DISORDERS | QLT USA, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| CN-1464880-A | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-12-31 | — | — | CN | disclosed |
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-1313751-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |
| WO-2002016380-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2002-02-28 | — | — | WO | disclosed |
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |