Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | THPO | P40225 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | NPY1R | P25929 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | NPY2R | P49146 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801134 | 1.00 | LMNA (0.73) | LMNACYP1A2THPOALDH1A1GLA | |
| SCHEMBL5389974 | 1.00 | LMNA (0.73) | LMNACYP1A2THPOALDH1A1GLA | |
| SCHEMBL5384030 | 0.88 | ADORA1 (0.68) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL3947524 | 0.88 | ADORA1 (0.68) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL4808305 | 0.88 | CYP1A2 (0.73) | LMNACYP1A2THPOALDH1A1GLA | |
| SCHEMBL7076252 | 0.87 | ADORA1 (0.62) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL3949755 | 0.87 | ADORA1 (0.62) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL5390238 | 0.87 | ADORA1 (0.62) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL7076255 | 0.87 | ADORA1 (0.62) | LMNACYP1A2RXFP1MAPK1ADORA1 | |
| SCHEMBL31602192 | 0.86 | ADORA3 (0.60) | LMNACYP1A2RXFP1MAPK1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414837-B1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS INC (US) | 2005-10-19 | — | — | EP | disclosed |