Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23311099 | 1.00 | NR1H2 (0.32) | NR1H2FKBP1A | |
| SCHEMBL51492 | 1.00 | NR1H2 (0.32) | NR1H2FKBP1A | |
| SCHEMBL62608 | 0.93 | FKBP1A (0.35) | FKBP1A | |
| SCHEMBL1147997 | 0.89 | FKBP1A (0.33) | NR1H2FKBP1A | |
| SCHEMBL31645669 | 0.89 | EPHX2 (0.34) | NR1H2FKBP1A | |
| SCHEMBL926420 | 0.89 | FKBP1A (0.33) | NR1H2FKBP1A | |
| SCHEMBL8062803 | 0.82 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL12632024 | 0.82 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL24166791 | 0.82 | LRRK2 (0.33) | FKBP1A | |
| SCHEMBL24166320 | 0.82 | LRRK2 (0.33) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129398-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090253677-A1 | HIV Integrase Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253677-A1 | HIV Integrase Inhibitors | DNTT, POLB, UNG | NR1H2 2220/4885FKBP1A 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.