SCHEMBL6260832

SCHEMBL6260832

CCN(CC)c1ccc(/C=N/N(c2ccccc2)c2cccc3ccccc23)cc1.CCN(CC)c1ccc(/C=N/N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.48
MAPK1 P28482 5/20 0.48
GAA P10253 4/20 0.48
HTT P42858 2/20 0.48
ALDH1A1 P00352 10/20 0.43
KDM4E B2RXH2 7/20 0.43
ESRRG P62508 1/20 0.42
KMT2A Q03164 9/20 0.41
MEN1 O00255 8/20 0.41
HPGD P15428 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 5/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5921967 0.99 MAPT (0.46) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL5921965 0.99 MAPT (0.46) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL16745300 0.89 APP (0.38) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL122070 0.85 MAPT (0.61) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL122069 0.85 MAPT (0.61) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL9775478 0.85 KMT2A (0.45) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL9775481 0.85 KMT2A (0.45) MAPTMAPK1GAAHTTALDH1A1
SCHEMBL13855340 0.85 SIGMAR1 (0.43) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL9775460 0.85 ALDH1A1 (0.49) MAPTMAPK1GAAALDH1A1KDM4E
SCHEMBL9775459 0.85 ALDH1A1 (0.49) MAPTMAPK1GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0928989-B1 Electrophotographic photosensitive member, process for producing electrophotographic photosensitive member, and process cartridge and electophotographic apparatus which have the electrophotographic photosensitive member CANON KK (JP) 2005-10-05 EP disclosed
EP-0928989-A1 Electrophotographic photosensitive member, process for producing electrophotographic photosensitive member, and process cartridge and electophotographic apparatus which have the electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 1999-07-14 EP disclosed