SCHEMBL6260907

SCHEMBL6260907

CC(O)CN(CCNCCN(CC(C)O)CC(C)O)CC(C)O

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
TSHR P16473 2/20 0.32
RECQL P46063 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14980610 0.98 KDM4E (0.32) KDM4EKMT2AATMTSHRRECQL
SCHEMBL24572104 0.98 KDM4E (0.32) KDM4EKMT2AATMTSHRRECQL
SCHEMBL10884117 0.89 CYP2C19 (0.48) KDM4EKMT2ATSHRRECQLCYP2C9
SCHEMBL14980608 0.89 KMT2A (0.36) KMT2ACYP2C19
SCHEMBL24570150 0.89 KMT2A (0.36) KMT2ACYP2C19
SCHEMBL24525598 0.89 KMT2A (0.36) KMT2ACYP2C19
SCHEMBL6262871 0.89 KMT2A (0.36) KMT2ACYP2C19
SCHEMBL2536610 0.89 KMT2A (0.34) KDM4EKMT2ACYP2C19
SCHEMBL14980609 0.88 CYP2C19 (0.47) KDM4EKMT2ARECQLCYP2C9CYP2C19
SCHEMBL21702542 0.88 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230105685-A1 POLYURETHANE COMPOSITIONS, PRODUCTS PREPARED WITH SAME AND PREPARATION METHODS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-06 US claimed
US-20230105685-A1 POLYURETHANE COMPOSITIONS, PRODUCTS PREPARED WITH SAME AND PREPARATION METHODS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-06 US disclosed
EP-1283228-B1 THERMOSETTING COMPOSITION SUNSTAR ENGINEERING INC (JP) 2005-11-09 EP disclosed
US-6809147-B1 ACRYLIC PLASTISOL, BLOCKED URETHANE PREPOLYMER AND LATENT CURING AGENT; STORAGE STABILITY; AUTOMOTIVE SEALERS OR UNDERCOATS SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2004-10-26 US disclosed
EP-1283228-A1 THERMOSETTING COMPOSITION SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2003-02-12 EP disclosed
EP-0094196-B1 TWO-COMPONENT URETHANE COATING SYSTEM The Lubrizol Corporation (US) 1986-08-27 EP disclosed
US-4436855-A DIISOCYANATE AND ORGANIC PHOSPHATE THE LUBRIZOL CORPORATION (US) 1984-03-13 US disclosed