Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884117 | 0.98 | CYP2C19 (0.48) | CYP2C19CYP2C9CA12CA6CA7 | |
| Edetol SCHEMBL25180337 | 0.94 | CA12 (0.44) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL15968113 | 0.91 | CYP2C9 (0.45) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL14980610 | 0.90 | KDM4E (0.32) | CYP2C19CYP2C9KDM4ERECQLKMT2A | |
| SCHEMBL24572104 | 0.90 | KDM4E (0.32) | CYP2C19CYP2C9KDM4ERECQLKMT2A | |
| SCHEMBL6260907 | 0.88 | KDM4E (0.33) | CYP2C19CYP2C9TDP1KDM4ERECQL | |
| SCHEMBL19832996 | 0.87 | CYP2C9 (0.39) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL22842379 | 0.85 | TDP1 (0.41) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL10379393 | 0.84 | CYP2C19 (0.56) | CYP2C19CYP2C9CA12CA6CA7 | |
| Edetol SCHEMBL9682893 | 0.83 | CYP2C9 (0.36) | CYP2C19CYP2C9CA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844028-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190177289-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-13 | — | — | US | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-23 | — | — | US | disclosed |
| US-8969353-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CYP2C19 1032/4885CYP2C9 1173/4885CA12 4669/4885 |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CYP2C19 1032/4885CYP2C9 1173/4885CA12 4669/4885 |
| US-20190177289-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CYP2C19 1032/4885CYP2C9 1173/4885CA12 4669/4885 |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | CYP2C19 1032/4885CYP2C9 1173/4885CA12 4669/4885 |
| US-10844028-B2 | Aminoalcohol lipidoids and uses thereof | PHOSPHO1, PNMT, AASDHPPT | CYP2C19 1032/4885CYP2C9 1173/4885CA12 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.