SCHEMBL626129

SCHEMBL626129

CCCC(=O)[N]C(=O)CCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.50
CES1 P23141 6/20 0.50
HDAC3 O15379 4/20 0.47
HDAC1 Q13547 4/20 0.47
HDAC2 Q92769 4/20 0.47
HDAC8 Q9BY41 4/20 0.47
FFAR3 O14843 3/20 0.47
TSHR P16473 3/20 0.45
ALDH1A1 P00352 3/20 0.43
HDAC6 Q9UBN7 1/20 0.41
CTSD P07339 1/20 0.39
AKR1B1 P15121 1/20 0.35
TP53 P04637 1/20 0.35
PPARG P37231 3/20 0.33
PPARD Q03181 3/20 0.33
PPARA Q07869 3/20 0.33
GPR84 Q9NQS5 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6975600 0.91 ALDH1A1 (0.43) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL6961963 0.89 CES1 (0.50) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL8013076 0.87 CES2 (0.52) CES2CES1TSHRALDH1A1AKR1B1
SCHEMBL3789226 0.85
SCHEMBL6973600 0.85
SCHEMBL543757 0.81 CES1 (0.55) CES2CES1TSHRALDH1A1AKR1B1
SCHEMBL175600 0.79 CES2 (0.57) CES2CES1TSHRALDH1A1AKR1B1
SCHEMBL6962993 0.79 CES2 (0.38) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL1796161 0.78
SCHEMBL42694 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed
EP-3421454-B1 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-04-05 EP disclosed
CN-108884044-B Piperidine derivatives 大塚制药株式会社 2023-01-31 CN disclosed
EP-4024486-A1 ORGANIC PHOTOELECTRIC CONVERSION MATERIAL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2022-07-06 EP disclosed
CN-114514621-A Photoelectric conversion element 住友化学株式会社 2022-05-17 CN disclosed
CN-111263984-B Photoelectric conversion element and method for manufacturing same 住友化学株式会社 2021-12-10 CN disclosed
CN-113169277-A Method for manufacturing organic photoelectric conversion element 住友化学株式会社 2021-07-23 CN disclosed
US-11069869-B2 Photoelectric conversion element and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-07-20 US disclosed
CN-112771685-A Photoelectric conversion element and method for manufacturing same 住友化学株式会社 2021-05-07 CN disclosed
US-10991842-B2 Photoelectric conversion element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-27 US disclosed
US-5312917-A Polyamide fiber stabilizers CIBA-GEIGY CORPORATION (US) 1994-05-17 US disclosed
EP-0187521-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-03-21 EP disclosed
EP-0214708-B1 GRISEOLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE SANKYO COMPANY LIMITED (JP) 1989-12-13 EP disclosed
EP-0143557-B1 GRISEOLIC ACID DERIVATIVES, AND THEIR USE SANKYO COMPANY LIMITED (JP) 1988-12-21 EP disclosed
US-4675275-A COLORFAST MAGENTA COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-06-23 US disclosed
EP-0214708-A2 Griseolic acid derivatives, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-03-18 EP disclosed
US-4634706-A BRAIN METABOLISM SANKYO COMPANY LIMITED (JP) 1987-01-06 US disclosed
EP-0187521-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-07-16 EP disclosed
EP-0143557-A2 Griseolic acid derivatives, and their use SANKYO COMPANY LIMITED (JP) 1985-06-05 EP disclosed
US-4205169-A N-[4-Azido-5-(2-ethoxyethyl)-6-phenyl-2-pyrimidinyl]acetamide and congeners G. D. SEARLE & CO. (US) 1980-05-27 US disclosed