Glutamine

Glutamine

SCHEMBL626142

NC(=O)CC[C@H](N)C(=O)O.OCC(O)CS

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.66
BLM P54132 1/20 0.66
PMP22 Q01453 1/20 0.66
KMT2A Q03164 1/20 0.66
GRM8 O00222 2/20 0.47
GRM6 O15303 2/20 0.47
GRM7 Q14831 2/20 0.47
GRM4 Q14833 2/20 0.47
GSR P00390 2/20 0.47
SLC1A1 P43005 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
CYP1A2 P05177 1/20 0.47
GRIK1 P39086 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL28491842 0.89 KMT2A (0.76) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL8037581 0.89 KMT2A (0.76) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL2129419 0.83 ALOX15 (0.79) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL285916 0.83 ALOX15 (0.79) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL285915 0.83 ALOX15 (0.79) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL1628897 0.82 KMT2A (0.76) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL2305257 0.82 KMT2A (0.76) ALOX15BLMPMP22KMT2AGRM8
Cysteine SCHEMBL3396289 0.81 PTGS1 (0.70) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL7559920 0.81 KMT2A (0.83) ALOX15BLMPMP22KMT2AGRM8
Glutamine SCHEMBL3178188 0.81 KMT2A (0.83) ALOX15BLMPMP22KMT2AGRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726630-B1 METHODS FOR DETERMINING DEVELOPMENTAL STAGE OF HUMAN CUMULUS CELLS INST NAT SANTE RECH MED (FR) 2021-06-16 EP disclosed
EP-2603581-B1 Cocultures of cumulus cells and embryos during in vitro fertilization procedures INST NAT SANTE RECH MED (FR) 2019-07-17 EP disclosed
US-9481863-B2 Methods for determining developmental stage of human cumulus cells INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-11-01 US disclosed
US-9365820-B2 Methods of growing an embryo to a blastocyst stage of development INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2016-06-14 US disclosed
US-20150079674-A1 METHODS OF GROWING AN EMBRYO TO A BLASTOCYST STAGE OF DEVELOPMENT UNIVERSITÉ DE MONTPELLIER (FR) 2015-03-19 US disclosed
US-8956865-B2 Methods of growing an embryo to a blastocyst stage of development INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2015-02-17 US disclosed
EP-2603581-A1 METHODS OF GROWING AN EMBRYO TO A BLASTOCYST STAGE OF DEVELOPMENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2013-06-19 EP disclosed
US-20130143317-A1 METHODS OF GROWING AN EMBRYO TO A BLASTOCYTE STAGE OF DEVELOPMENT INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2013-06-06 US disclosed
WO-2013004612-A1 METHODS FOR DETERMINING DEVELOPMENTAL STAGE OF HUMAN CUMULUS CELLS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2013-01-10 WO disclosed
WO-2012020077-A1 METHODS OF GROWING AN EMBRYO TO A BLASTOCYST STAGE OF DEVELOPMENT INSERM (INSTITUT MATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (FR) 2012-02-16 WO disclosed