Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPX4 | P36969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626162 | 0.79 | CD38 (0.34) | GPX4 | |
| SCHEMBL626604 | 0.77 | FYN (0.35) | — | |
| SCHEMBL626146 | 0.68 | — | — | |
| SCHEMBL2250791 | 0.63 | MKNK1 (0.53) | — | |
| SCHEMBL1652361 | 0.60 | F13A1 (0.39) | — | |
| SCHEMBL571765 | 0.59 | GRIN2B (0.71) | — | |
| SCHEMBL3480924 | 0.57 | KDM1A (0.53) | — | |
| SCHEMBL7323659 | 0.57 | POLB (0.67) | — | |
| SCHEMBL453907 | 0.57 | — | — | |
| SCHEMBL7024181 | 0.57 | KCNH2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |