Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 12/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626147 | 0.77 | GPX4 (0.31) | — | |
| SCHEMBL21047804 | 0.64 | KDM4E (0.62) | — | |
| SCHEMBL21047693 | 0.63 | NOS2 (0.51) | — | |
| SCHEMBL21047854 | 0.61 | NPC1 (0.50) | — | |
| SCHEMBL21047562 | 0.60 | FDPS (0.37) | FYNPIM1 | |
| SCHEMBL28283911 | 0.60 | SYK (0.39) | PIM1 | |
| SCHEMBL21047605 | 0.60 | EPHX2 (0.36) | PIM1 | |
| SCHEMBL21047645 | 0.58 | MEN1 (0.42) | PIM1 | |
| SCHEMBL21047563 | 0.57 | PIM1 (0.30) | PIM1 | |
| SCHEMBL17101636 | 0.57 | MAPK1 (0.62) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |