Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.71 |
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903300 | 0.83 | PTPN1 (1.00) | PTPN1PTPRCPTPN2 | |
| SCHEMBL476321 | 0.73 | PTPN1 (0.61) | PTPN1PTPRCPTPN2GPR35 | |
| SCHEMBL6266960 | 0.72 | PTPN1 (0.68) | PTPN1PTPRCPTPN2GPR35 | |
| SCHEMBL6262341 | 0.70 | PTPN1 (0.76) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907174 | 0.70 | PTPN1 (0.76) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3913634 | 0.69 | PTPN1 (0.56) | PTPN1PTPRCPTPN2GPR35 | |
| SCHEMBL6267108 | 0.69 | PTPN1 (0.75) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3906716 | 0.68 | PTPN1 (0.71) | PTPN1PTPRCPTPN2 | |
| SCHEMBL6262512 | 0.67 | PTPN1 (0.40) | PTPN1 | |
| SCHEMBL4582179 | 0.67 | GPR35 (0.54) | PTPN1PTPRCPTPN2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |