SCHEMBL6262175

SCHEMBL6262175

CC(C)C1=Cc2ccccc2OC12C=Cc1ccc(N(Cc3ccccc3)Cc3ccccc3)cc1O2

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.36
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
HIF1A Q16665 4/20 0.33
EPAS1 Q99814 4/20 0.33
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
QPCT Q16769 1/20 0.30
CNR2 P34972 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765040 1.00 CYP2C19 (0.36) CYP2C19CRHBPCRHR2HIF1AEPAS1
SCHEMBL10849196 0.89 CA12 (0.33)
SCHEMBL6701609 0.83 CYP2C19 (0.35) CYP2C19CRHBPCRHR2HIF1AEPAS1
SCHEMBL11538450 0.80 CYP2C19 (0.34) CYP2C19CRHBPCRHR2HIF1AEPAS1
SCHEMBL11268720 0.79 CYP2C19 (0.34) CYP2C19CRHBPCRHR2HIF1AEPAS1
SCHEMBL11586208 0.74 CA12 (0.35) HIF1AEPAS1HTT
SCHEMBL3877465 0.74 CA12 (0.33) HIF1AEPAS1HTTCNR2
SCHEMBL10618065 0.74 CA12 (0.33) HIF1AEPAS1HTTCNR2
SCHEMBL9333313 0.71 HTR2C (0.32)
SCHEMBL11280803 0.70 CA12 (0.35) HIF1AEPAS1HTTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573210-B2 Pressure-sensitive record material ARJO WIGGINS LTD (GB) 2005-11-23 EP disclosed
EP-1054776-B1 USE OF ALKOXYLATED FATTY ACID LOW ALKYL ESTERS COGNIS DEUTSCHLAND GMBH (DE) 2002-04-10 EP disclosed
EP-1054776-A2 USE OF ALKOXYLATED FATTY ACID LOW ALKYL ESTERS Cognis Deutschland GmbH (DE) 2000-11-29 EP disclosed
WO-1999002349-A2 USE OF ALKOXYLATED FATTY ACID LOW ALKYL ESTERS COGNIS DEUTSCHLAND GMBH (DE) 1999-01-21 WO disclosed
EP-0573210-B1 Pressure-sensitive record material ARJO WIGGINS LTD (GB) 1998-10-28 EP disclosed
EP-0593192-B1 Chromogenic composition for use in pressure-sensitive record material WIGGINS TEAPE GROUP LTD (GB) 1997-03-26 EP disclosed
EP-0520639-B1 Solvent compositions for use in pressure-sensitive copying paper WIGGINS TEAPE GROUP LTD (GB) 1996-12-18 EP disclosed
US-5478380-A Comprising methyl palmitate and/or fatty acid esters vehicle THE WIGGINS TEAPE GROUP LIMITED (GB) 1995-12-26 US disclosed
US-5472489-A Mixture of vegetable oil and fatty acid ester THE WIGGINS TEAPE GROUP LIMITED (GB) 1995-12-05 US disclosed
US-5464803-A Chromogenic composition for use in pressure-sensitive record material comprises chromogen in vegetable oil vehicle which is high melting and solid or semisolid at ambient temperatures and free of specified ester of nonaromatic monocarboxylic acid THE WIGGINS TEAPE GROUP LIMITED (GB) 1995-11-07 US disclosed
EP-0593192-A2 Chromogenic composition for use in pressure-sensitive record material The Wiggins Teape Group Limited (GB) 1994-04-20 EP disclosed
US-5281266-A Vegetable oil, mono- or di-functional ester of nonaromatic carboxylic acid THE WIGGINS TEAPE GROUP LIMITED (GB) 1994-01-25 US disclosed
EP-0573210-A2 Pressure-sensitive record material The Wiggins Teape Group Limited (GB) 1993-12-08 EP disclosed
EP-0520639-A1 Solvent compositions for use in pressure-sensitive copying paper The Wiggins Teape Group Limited (GB) 1992-12-30 EP disclosed
US-5130289-A Carbonless paper with calcium sulfate THE WIGGINS TEAPE GROUP LIMITED (GB) 1992-07-14 US disclosed
EP-0429239-A1 Record material utilising a vinyl carbinol or derivative thereof as a chromogenic compound The Wiggins Teape Group Limited (GB) 1991-05-29 EP disclosed
EP-0311380-B1 PRESSURE SENSITIVE RECORD MATERIAL The Wiggins Teape Group Limited (GB) 1991-05-08 EP disclosed
EP-0311380-A1 Pressure sensitive record material The Wiggins Teape Group Limited (GB) 1989-04-12 EP disclosed