Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701609 | 0.92 | CYP2C19 (0.35) | CYP2C19CRHBPCRHR2TSHRHIF1A | |
| SCHEMBL11259985 | 0.90 | CA12 (0.33) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11264128 | 0.90 | CA12 (0.33) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9333313 | 0.87 | HTR2C (0.32) | — | |
| SCHEMBL11280803 | 0.86 | CA12 (0.35) | HIF1AEPAS1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3877465 | 0.83 | CA12 (0.33) | HIF1AEPAS1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11269716 | 0.82 | HTR2C (0.41) | TSHRHIF1AEPAS1KMT2AMEN1 | |
| SCHEMBL6262175 | 0.79 | CYP2C19 (0.36) | CYP2C19CRHBPCRHR2TSHRHIF1A | |
| SCHEMBL8765040 | 0.79 | CYP2C19 (0.36) | CYP2C19CRHBPCRHR2TSHRHIF1A | |
| SCHEMBL11538450 | 0.74 | CYP2C19 (0.34) | CYP2C19CRHBPCRHR2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345073-A | 7,7'-Diamino derivatives of 2,2'-spirodibenzopyranes | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| US-4316027-A | DYE INTERMEDIATES USED IN THE MANUFACTURE OF PRESSURE SENSITIVE RECORDING MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4110348-A | PRESSURE SENSITIVE RECORDING | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |