Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765046 | 0.96 | PTGS2 (0.67) | PTGS2PTGS1LMNANPSR1CA1 | |
| SCHEMBL8765473 | 0.95 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8765227 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1LMNANPSR1KDM4E | |
| SCHEMBL8633382 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1LMNANPSR1CA1 | |
| SCHEMBL8765541 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8765203 | 0.83 | PTGS2 (0.65) | PTGS2PTGS1LMNANPSR1KDM4E | |
| SCHEMBL3245704 | 0.83 | PTGS2 (0.80) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL213767 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8765024 | 0.83 | RAB9A (0.69) | PTGS2PTGS1LMNANPSR1KDM4E | |
| SCHEMBL6405376 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044194-A2 | TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR | PHARMACIA CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |