Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 5/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546515 | 0.83 | HMGB1 (0.53) | NOTUMKDM4EMEN1KMT2AXDH | |
| SCHEMBL8658135 | 0.83 | KDM4E (0.41) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL19358017 | 0.81 | NOTUM (0.39) | NOTUMKDM4EMEN1KMT2AXDH | |
| SCHEMBL29669953 | 0.81 | KDM4E (0.59) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL951068 | 0.81 | KDM4E (0.59) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL23699472 | 0.81 | NOTUM (0.39) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| Ethane SCHEMBL28184948 | 0.80 | KDM4E (0.58) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL11520049 | 0.79 | KDM4E (0.43) | NOTUMKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27496792 | 0.79 | GPR35 (0.49) | NOTUMKDM4ETDP1XDHSLC22A12 | |
| SCHEMBL3758179 | 0.78 | CYP3A4 (0.45) | NOTUMKDM4EMEN1KMT2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583965-A1 | METHOD FOR DETERMINING MOLECULAR AFFINITIES FOR HUMAN SERUM ALBUMIN | Pharmacia & Upjohn Company LLC (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20050003449-A1 | Method for determining molecular affinities for human serum albumin | PHARMACIA & UPJOHN COMPANY | 2005-01-06 | — | — | US | disclosed |
| WO-2004063749-A1 | METHOD FOR DETERMINING MOLECULAR AFFINITIES FOR HUMAN SERUM ALBUMIN | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-07-29 | — | — | WO | disclosed |