SCHEMBL951068

SCHEMBL951068

Cc1cc(C#N)cc(C(=O)O)c1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40
GABRG1 Q8N1C3 1/20 0.40
GABRG3 Q99928 1/20 0.40
GABRQ Q9UN88 1/20 0.40
NOTUM Q6P988 2/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669953 1.00 KDM4E (0.59) KDM4EGABRPGABRDGABRA1GABRB1
Ethane SCHEMBL28184948 0.98 KDM4E (0.58) KDM4EGABRPGABRDGABRA1GABRB1
Hexane SCHEMBL28184950 0.91 KDM4E (0.50) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL21990971 0.86 KDM4E (0.42) KDM4EKMT2AMEN1GPR35HTT
SCHEMBL19125812 0.86 KDM4E (0.42) KDM4ETDP1TTRALB
SCHEMBL31432230 0.86 KDM4E (0.42) KDM4ETDP1TTRALB
SCHEMBL6263161 0.81 NOTUM (0.41) KDM4ENOTUMKMT2AMEN1TDP1
SCHEMBL25300437 0.81 KDM4E (0.39) KDM4EGPR35HTTTTRALB
SCHEMBL14645844 0.81 ALDH1A1 (0.49) KDM4EGPR35
SCHEMBL635493 0.81 KDM4E (0.39) KDM4EGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920277-B VHH-ELISA kit for analyzing cyantraniliprole and chlorantraniliprole residues and application thereof 中国农业大学 2022-08-09 CN claimed
EP-2729444-B1 METHOD FOR MANUFACTURING 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE BAYER IP GMBH (DE) 2017-08-23 EP claimed
US-9169198-B2 Method for the production of 2-amino-5-cyano-N,3-dimethylbenzamide BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-27 US claimed
US-20140148611-A1 METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-29 US claimed
WO-2026099847-A1 SYNTHESIS OF CYANO-ANTHRANILIC ACID ADAMA MAKHTESHIM LTD. (IL) 2026-05-15 WO disclosed
WO-2026099847-A1 SYNTHESIS OF CYANO-ANTHRANILIC ACID ADAMA MAKHTESHIM LTD. (IL) 2026-05-15 WO disclosed
US-12331028-B2 Process for preparation of Anthranilamides UPL LTD (IN) 2025-06-17 US disclosed
EP-3902792-B1 PROCESS FOR PREPARATION OF ANTHRANILAMIDES UPL LTD (IN) 2025-05-21 EP disclosed
WO-2025049326-A1 TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 BIOCRYST PHARMACEUTICALS, INC. (US) 2025-03-06 WO disclosed
CN-119431187-A Preparation method of key intermediate of chlorantraniliprole 山东垄喜植物保护有限公司 2025-02-14 CN disclosed
US-12221436-B2 Anthranilamides, their use as insecticide and processes for preparing the same PI INDUSTRIES LTD. (IN) 2025-02-11 US disclosed
US-20240327395-A1 A PROCESS FOR PREPARING BENZOXAZINONE COMPOUNDS TAGROS CHEMICALS INDIA PVT LTD (IN) 2024-10-03 US disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
EP-1771070-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-04-11 EP disclosed
EP-1751112-A2 ANTHRANILAMIDE INSECTICIDES E.I.Du pont de nemours and company (US) 2007-02-14 EP disclosed
WO-2006068669-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-29 WO disclosed
WO-2006023783-A1 NOVEL ANTHRANILAMIDES USEFUL FOR CONTROLLING INVERTEBRATE PESTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-02 WO disclosed
WO-2005118552-A2 ANTHRANILAMIDE INSECTICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-12-15 WO disclosed
US-20050113450-A1 Antibacterial agents PHARMACIA & UPJOHN COMPANY 2005-05-26 US disclosed
WO-2004018414-A2 ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113450-A1 Antibacterial agents CLPP, SPOUT1, SAMHD1 KDM4E 2637/4885GABRP 3873/4885GABRD 2221/4885
US-20140148611-A1 METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE ALKBH5, ALKBH2, MMAB KDM4E 124/4885GABRP 1406/4885GABRD 1068/4885
US-12221436-B2 Anthranilamides, their use as insecticide and processes for preparing the same CYP1A2, ANTXR2, DDT KDM4E 1143/4885GABRP 2497/4885GABRD 2391/4885
US-20240327395-A1 A PROCESS FOR PREPARING BENZOXAZINONE COMPOUNDS XDH, PDHX, CYP11B1 KDM4E 1398/4885GABRP 516/4885GABRD 428/4885
US-12331028-B2 Process for preparation of Anthranilamides NAAA, ANTXR2, AADAC KDM4E 898/4885GABRP 3165/4885GABRD 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.