Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 0.58 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404756 | 0.89 | HTR4 (0.58) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| Hydrochloric Acid SCHEMBL7399150 | 0.88 | HTR2C (0.59) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL7398776 | 0.84 | HTR4 (0.43) | HTR4SIGMAR1ACHE | |
| SCHEMBL7401627 | 0.84 | HTR4 (0.56) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL7400000 | 0.81 | HTR4 (0.58) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL4151143 | 0.81 | HTR4 (0.46) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL8317708 | 0.81 | HTR4 (0.44) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL7391971 | 0.80 | HTR4 (0.45) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL7395285 | 0.79 | HTR4 (0.42) | HTR4HTR2CADRA2CHTR1DADRA1A | |
| SCHEMBL6776570 | 0.77 | HTR4 (0.45) | HTR4HTR2CADRA2CHTR1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556489-A1 | PHARMACEUTICAL COMPOSITION FOR PREPARING A MEDICINE FOR TREATING AND/OR PREVENTING A PATHOLOGY RELATED TO AN OBSESSIVE BEHAVIOUR OR OBESITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004042063-A1 | PHARMACEUTICAL COMPOSITION FOR PREPARING A MEDICINE FOR TREATING AND/OR PREVENTING A PATHOLOGY RELATED TO AN OBSESSIVE BEHAVIOUR OR OBESITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS- (FR) | 2004-05-21 | — | — | WO | disclosed |