Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | XDH | P47989 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790393 | 0.78 | NPC1 (1.00) | RAB9AXDHHTTLMNAKDM4E | |
| SCHEMBL29306049 | 0.77 | RAB9A (0.98) | RAB9AHTTLMNAKDM4ENPC1 | |
| SCHEMBL27822388 | 0.77 | NPC1 (0.74) | RAB9AXDHHTTLMNAKDM4E | |
| SCHEMBL6271125 | 0.74 | MAPT (0.82) | RAB9ALMNAKDM4EPIP4K2AMAPT | |
| SCHEMBL26781491 | 0.74 | HPGD (1.00) | RAB9ALMNAKDM4ENPC1PIP4K2A | |
| SCHEMBL6265665 | 0.74 | RAB9A (0.54) | RAB9AHTTLMNAKDM4ENPC1 | |
| SCHEMBL26781483 | 0.74 | TP53 (0.72) | RAB9AHTTLMNAKDM4ENPC1 | |
| SCHEMBL31615171 | 0.74 | HPGD (0.82) | RAB9ALMNAKDM4ENPC1PIP4K2A | |
| SCHEMBL6267014 | 0.73 | KDM4E (0.71) | RAB9ALMNAKDM4EPIP4K2AMAPT | |
| SCHEMBL6266576 | 0.73 | KDM4E (0.77) | RAB9AHTTLMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | claimed |
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |