Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.76 |
| ▸ | TP53 | P04637 | 11/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268635 | 0.86 | MAPT (1.00) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL6264705 | 0.84 | MAPT (0.75) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL6270710 | 0.81 | MAPT (0.71) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL6264746 | 0.79 | MAPT (0.64) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL17474420 | 0.78 | MAPT (1.00) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL6268057 | 0.76 | TP53 (0.71) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL6267962 | 0.76 | MAPT (0.56) | MAPTTP53ALDH1A1LMNAPOLB | |
| SCHEMBL17474394 | 0.71 | MAPT (0.84) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL23579671 | 0.71 | KDM4E (0.75) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL30032758 | 0.71 | KDM4E (0.75) | MAPTTP53ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |