Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264705 | 0.89 | MAPT (0.75) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6264746 | 0.86 | MAPT (0.64) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL17474420 | 0.83 | MAPT (1.00) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6263779 | 0.81 | MAPT (0.76) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6268635 | 0.80 | MAPT (1.00) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6266847 | 0.76 | TP53 (0.55) | MAPTALDH1A1KDM4ETP53LMNA | |
| SCHEMBL23579671 | 0.76 | KDM4E (0.75) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL30032758 | 0.76 | KDM4E (0.75) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL8344398 | 0.74 | LMNA (0.67) | MAPTALDH1A1KDM4EGAATP53 | |
| SCHEMBL6268057 | 0.74 | TP53 (0.71) | MAPTALDH1A1KDM4EGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |