Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270710 | 0.89 | MAPT (0.71) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6268057 | 0.86 | TP53 (0.71) | MAPTALDH1A1KDM4EGAATP53 | |
| SCHEMBL17474420 | 0.85 | MAPT (1.00) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6267014 | 0.84 | KDM4E (0.71) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6263779 | 0.84 | MAPT (0.76) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6268682 | 0.80 | KDM4E (0.65) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6264746 | 0.79 | MAPT (0.64) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6268635 | 0.79 | MAPT (1.00) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL26781491 | 0.78 | HPGD (1.00) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL31615171 | 0.78 | HPGD (0.82) | MAPTALDH1A1KDM4EGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |