Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 known ✓ | P08588 | 3/20 | 0.43 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.43 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.43 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.43 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL21225308 | 0.98 | ICAM1 (0.45) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL1678480 | 0.98 | ICAM1 (0.47) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL11324839 | 0.97 | ICAM1 (0.46) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL1074745 | 0.97 | ICAM1 (0.46) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL9770145 | 0.97 | ICAM1 (0.46) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL11031379 | 0.93 | ALDH1A1 (0.46) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Ethylene SCHEMBL173231 | 0.89 | ALDH1A1 (0.49) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| SCHEMBL4296256 | 0.89 | ICAM1 (0.44) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL5907714 | 0.89 | HRH1 (0.46) | ICAM1SELEVCAM1ALDH1A1KDM4E | |
| SCHEMBL15951404 | 0.87 | ICAM1 (0.43) | ICAM1SELEVCAM1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948997-B1 | Manufacturing method of absorbent resin | NIPPON CATALYTIC CHEM IND (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6291636-B1 | DRYING HYDROGEL OF A CROSSLINKED POLYMER; PULVERIZING; SEPARATING | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0948997-A2 | Manufacturing method of absorbent resin | Nippon Shokubai Co., Ltd. (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0379174-A2 | 2,3-Dihydro-3,3-dimethyl-5-trifluoromethanesulfonyloxybenzofurans, process for producing them and herbicides containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-07-25 | — | — | EP | disclosed |