Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020498 | 0.88 | MRGPRX4 (0.47) | MRGPRX4KDM4EALDH1A1GAALMNA | |
| SCHEMBL11290182 | 0.87 | KDM4E (0.48) | MRGPRX4KDM4EALDH1A1GAALMNA | |
| SCHEMBL11295569 | 0.86 | KDM4E (0.47) | MRGPRX4KDM4EALDH1A1GAALMNA | |
| SCHEMBL956571 | 0.85 | LMNA (0.60) | MRGPRX4KDM4EALDH1A1GAALMNA | |
| SCHEMBL11289835 | 0.83 | LMNA (0.54) | MRGPRX4KDM4EALDH1A1GAALMNA | |
| SCHEMBL6260288 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1LMNAPPARG | |
| Dechloroetomoxir SCHEMBL10436254 | 0.81 | ABCB11 (0.54) | LMNAL3MBTL1KCNA3 | |
| Dechloroetomoxir SCHEMBL6262443 | 0.81 | ABCB11 (0.54) | LMNAL3MBTL1KCNA3 | |
| SCHEMBL10436502 | 0.81 | ABCB11 (0.54) | LMNAL3MBTL1KCNA3 | |
| SCHEMBL11297445 | 0.81 | HRH3 (0.50) | KDM4EALDH1A1LMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275390-B1 | Medicament for treatment of heart failure | WOLF HORST P O (DE) | 2005-11-02 | — | — | EP | claimed |
| EP-0231367-B1 | USE OF OXIRANCARBOXYLIC ACIDS FOR THE TREATMENT OF HYPERLIPEMIA | Wolf, Horst P.O., Dr. (DE) | 1991-07-24 | — | — | EP | claimed |
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | claimed |