SCHEMBL6264147

SCHEMBL6264147

Cc1ccc(N(c2ccc(C)cc2)N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
ACHE P22303 2/20 0.53
LMNA P02545 1/20 0.53
ALOX12 P18054 1/20 0.53
CYP2C19 P33261 2/20 0.52
ALDH1A1 P00352 4/20 0.50
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
TDP1 Q9NUW8 3/20 0.44
HPGD P15428 1/20 0.44
TRPM8 Q7Z2W7 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MAPT P10636 2/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6269460 1.00 TSHR (0.53) TSHRACHELMNAALOX12CYP2C19
SCHEMBL11262611 0.88 ALDH1A1 (0.61) TSHRACHELMNAALOX12CYP2C19
SCHEMBL28995969 0.85 CYP2C19 (0.45) TSHRACHELMNAALOX12CYP2C19
SCHEMBL261308 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL13515157 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL43023 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL12154508 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL6139963 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL10065556 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19
SCHEMBL57176 0.83 ALDH1A1 (0.56) TSHRACHELMNAALOX12CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005087901-A2 FUEL ADDITIVE COMPOSITION HAVING ANTIKNOCK PROPERTIES INNOSPEC LIMITED (GB) 2005-09-22 WO claimed
CN-116964063-A Polycyclic aromatic compounds 学校法人关西学院 2023-10-27 CN disclosed
CN-116284073-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-06-23 CN disclosed
WO-2005087901-A2 FUEL ADDITIVE COMPOSITION HAVING ANTIKNOCK PROPERTIES INNOSPEC LIMITED (GB) 2005-09-22 WO disclosed
US-6444603-B1 CATALYST COMPONENT OBTAINED BY REACTING COMPOUND COMPRISING METAL OF GROUP 13 OF PERIODIC TABLE, COMPOUND CAPABLE OF BEING BONDED TO TWO OR MORE OF GROUP 13 METAL, COMPOUND CAPABLE OF FORMING IONIZING IONIC COMPOUND WITH GROUP 13 COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-09-03 US disclosed