SCHEMBL6264166

SCHEMBL6264166

CC(=O)c1ccc(-c2ccccc2)cn1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HIF1A Q16665 6/20 0.53
ALDH1A1 P00352 1/20 0.52
CTSA P10619 1/20 0.47
EGLN1 Q9GZT9 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SGK1 O00141 1/20 0.43
STK17B O94768 1/20 0.42
USP30 Q70CQ3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30443990 0.90 ALDH1A1 (0.50) HIF1AALDH1A1EGLN1STK17B
SCHEMBL14826038 0.85 EGLN1 (0.58) SMN1; SMN2HIF1AALDH1A1EGLN1STK17B
SCHEMBL29929320 0.84 HIF1A (0.55) HIF1AALDH1A1CTSA
SCHEMBL71034 0.84 HIF1A (0.55) HIF1AALDH1A1CTSA
SCHEMBL14838812 0.83 EGLN1 (0.42) MAPTSMN1; SMN2HIF1AALDH1A1CTSA
SCHEMBL14815618 0.83 GRIN1 (0.45) SMN1; SMN2HIF1AALDH1A1EGLN1USP30
Hydrochloric Acid SCHEMBL28470042 0.82 HIF1A (0.54) HIF1AALDH1A1CTSA
Ethylene SCHEMBL29031104 0.81 HIF1A (0.53) HIF1AALDH1A1CTSA
SCHEMBL2554720 0.81 HIF1A (0.56) HIF1ACTSAEGLN1MEN1KMT2A
SCHEMBL11047806 0.81 HIF1A (0.53) SMN1; SMN2HIF1ACTSAEGLN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed
WO-2024039250-A1 METHANOGEN INHIBITORS PASTORAL GREENHOUSE GAS RESEARCH LIMITED (NZ) 2024-02-22 WO disclosed
US-20230183229-A1 Compounds SYGNATURE DISCOVERY LIMITED (GB) 2023-06-15 US disclosed
US-20220223795-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2022-07-14 US disclosed
WO-2021045460-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-03-11 WO disclosed
WO-2005092304-A2 ANTIFUNGAL AGENTS F2G LTD (GB) 2005-10-06 WO disclosed
CN-1056840-C Oxime derivatives, their preparation and their therapeutic use SANKYO CO (JP) 2000-09-27 CN disclosed
CN-1143639-A Oxime derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1997-02-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183229-A1 Compounds UGT1A1, CYP1A1, CYP1B1 MAPT 2349/4885SMN1; SMN2 2367/4885HIF1A 445/4885
US-20220223795-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 MAPT 1857/4885SMN1; SMN2 3932/4885HIF1A 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.