Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.51 |
| ▸ | AR | P10275 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569801 | 0.77 | VDR (0.53) | VDRAR | |
| SCHEMBL5566469 | 0.75 | VDR (0.51) | VDRAR | |
| SCHEMBL5568949 | 0.71 | VDR (0.43) | VDRARKDM4EALDH1A1 | |
| SCHEMBL6440947 | 0.71 | VDR (0.44) | VDRAR | |
| SCHEMBL5861034 | 0.70 | PPARD (0.54) | KDM4E | |
| SCHEMBL5569422 | 0.70 | VDR (0.42) | VDRARKDM4EALDH1A1 | |
| SCHEMBL12868260 | 0.69 | VDR (0.70) | VDRARALDH1A1 | |
| SCHEMBL7181681 | 0.69 | VDR (1.00) | VDRAR | |
| SCHEMBL29754394 | 0.69 | VDR (1.00) | VDRAR | |
| SCHEMBL13712037 | 0.67 | VDR (0.73) | VDRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587905-A3 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1587905-A2 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004063348-A2 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |