SCHEMBL6264292

SCHEMBL6264292

C[C@@H](CN(CC(=O)O)C[C@H](Cc1ccc(N2C(=O)C=CC2=O)cc1)[N]CC(=O)O)NC(C(=O)O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.33
FAAH O00519 1/20 0.32
DDAH1 O94760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442862 0.84 MGLL (0.34) MGLLFAAHDDAH1
SCHEMBL442861 0.84 MGLL (0.34) MGLLFAAHDDAH1
SCHEMBL442863 0.69 MGLL (0.39) MGLLFAAHDDAH1
SCHEMBL1493211 0.69 NPC1 (0.38)
SCHEMBL440657 0.67 OPRM1 (0.34)
SCHEMBL440658 0.67 OPRM1 (0.34)
SCHEMBL438372 0.67 NPC1 (0.37)
SCHEMBL438371 0.67 NPC1 (0.37)
SCHEMBL438287 0.67 OPRM1 (0.39)
SCHEMBL437798 0.65 KMT2A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1590005-A1 CONJUGATES OF ENANTIOMER-PURE (4S,8S)- AND (4R,8R)-4-P-BENZYL-8-METHYL-3,6,9-TRIAZA- SP 3 /SP N, SP 6 /SP N, SP 9 /SP N-TRICARBOXYMETHYL-1,11-UNDECANOIC ACID WITH BIOMOLECULES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR PRODUCING PHARMACEUTICAL AGENTS Schering Aktiengesellschaft (DE) 2005-11-02 EP disclosed
WO-2004069282-A1 CONJUGATES OF ENANTIOMER-PURE (4S,8S)- AND (4R,8R)-4-P-BENZYL-8-METHYL-3,6,9-TRIAZA-3N,6N,9N-TRICARBOXYMETHYL-1,11-UNDECANOIC ACID WITH BIOMOLECULES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR PRODUCING PHARMACEUTICAL AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 2004-08-19 WO disclosed