SCHEMBL6264472

SCHEMBL6264472

[N-]=[N+]=CC(=O)CCCCCCCCCCCCC(=O)C=[N+]=[N-]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.52
ALDH1A1 P00352 4/20 0.47
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
POLB P06746 1/20 0.31
POLA1 P09884 1/20 0.31
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724562 0.97 FAAH (0.53) FAAHALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL11252256 0.92 FAAH (0.53) FAAHALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL11084332 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL6893226 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL11081119 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL13163885 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL11090505 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL6256065 0.89 FAAH (0.67) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL23113780 0.86 FAAH (0.69) FAAHALDH1A1TSHRPOLBPOLA1
SCHEMBL11263296 0.86 FAAH (0.47) FAAHALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6972343-B1 Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity CNRS (FR) 2005-12-06 US disclosed
EP-1196371-B1 QUATERNARY BIS-AMMONIUM SALT PRECURSORS AND THEIR USES AS PRODRUGS HAVING AN ANTIPARASITIC ACTIVITY CENTRE NAT RECH SCIENT (FR) 2005-11-02 EP disclosed
EP-1196371-A1 QUATERNARY BIS-AMMONIUM SALT PRECURSORS AND THEIR USES AS PRODRUGS HAVING AN ANTIPARASITIC ACTIVITY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-04-17 EP disclosed
WO-2001005742-A1 QUATERNARY BIS-AMMONIUM SALT PRECURSORS AND THEIR USES AS PRODRUGS HAVING AN ANTIPARASITIC ACTIVITY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2001-01-25 WO disclosed