Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 14/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626460 | 0.85 | MAPT (0.46) | FYNMMP13GPR119 | |
| SCHEMBL624532 | 0.83 | PIM1 (0.62) | FYN | |
| SCHEMBL624984 | 0.82 | PIK3CA (0.48) | FYNMKNK1 | |
| SCHEMBL627066 | 0.81 | KDM4E (0.46) | FYNMKNK1GPR119ACKR3 | |
| SCHEMBL626982 | 0.81 | FYN (0.56) | FYNMKNK1GPR119 | |
| SCHEMBL624057 | 0.81 | FYN (0.60) | FYNMKNK1 | |
| SCHEMBL628028 | 0.81 | FYN (0.56) | FYNMKNK1 | |
| SCHEMBL624885 | 0.80 | FYN (0.51) | FYNACKR3 | |
| SCHEMBL624884 | 0.80 | FYN (0.51) | FYNACKR3 | |
| SCHEMBL1945181 | 0.78 | FYN (0.87) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |