Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 10/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628028 | 0.87 | FYN (0.56) | FYNMKNK1PIM1KDM4EPKM | |
| SCHEMBL624057 | 0.87 | FYN (0.60) | FYNMKNK1PIM1 | |
| SCHEMBL624532 | 0.86 | PIM1 (0.62) | FYNPIM1 | |
| SCHEMBL626983 | 0.84 | CETP (0.44) | CETPGPR119KDM4EPKMPRMT5 | |
| SCHEMBL624036 | 0.81 | FYN (0.46) | FYNPIM1GPR119EGLN2 | |
| SCHEMBL623851 | 0.81 | FYN (0.61) | FYNMKNK1PIM1 | |
| SCHEMBL626459 | 0.81 | FYN (0.59) | FYNMKNK1GPR119 | |
| SCHEMBL27614055 | 0.80 | TGFBR1 (0.54) | CETPGPR119KDM4EPKM | |
| SCHEMBL627066 | 0.79 | KDM4E (0.46) | FYNMKNK1GPR119KDM4EPKM | |
| SCHEMBL624984 | 0.79 | PIK3CA (0.48) | FYNMKNK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |