⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264762 | 0.82 | — | — | |
| SCHEMBL6319582 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL6319649 | 0.71 | — | — | |
| SCHEMBL6316196 | 0.71 | ROCK2 (0.32) | — | |
| SCHEMBL6318624 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL6319046 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL6319894 | 0.68 | — | — | |
| SCHEMBL6319816 | 0.67 | PDE5A (0.32) | — | |
| SCHEMBL6321015 | 0.67 | CYP1A2 (0.34) | — | |
| SCHEMBL6325348 | 0.66 | GRIA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| WO-2005058330-A1 | PHOSPHORUS CONTAINING COMPOUNDS USEFUL FOR THE REGULATION OF LDL AND LP(A) LEVELS | QUATRX PHARMACEUTICALS CO. (US) | 2005-06-30 | — | — | WO | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |