Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | GOT1 | P17174 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520906 | 0.78 | IDO1 (0.58) | GPR17MTNR1AMTNR1BGOT1HDAC8 | |
| SCHEMBL734758 | 0.76 | GPR17 (0.68) | GPR17NPC1CYP2D6SLC6A4 | |
| SCHEMBL626655 | 0.76 | GPR17 (0.63) | GPR17TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL625920 | 0.76 | MTNR1A (0.76) | NOTUMMTNR1AMTNR1BMMP9MMP8 | |
| SCHEMBL6510028 | 0.74 | GPR17 (0.73) | GPR17MEN1KMT2APOLBTSHR | |
| SCHEMBL9279939 | 0.73 | GPR17 (0.62) | GPR17SLC6A4 | |
| SCHEMBL9731315 | 0.72 | GRIN1 (0.61) | GPR17GOT1NPC1RAB9AMEN1 | |
| SCHEMBL627038 | 0.71 | MEN1 (0.74) | NOTUMMTNR1ANPC1RAB9AMEN1 | |
| SCHEMBL7413409 | 0.71 | GPR17 (0.60) | GPR17HDAC8MEN1KMT2APOLB | |
| SCHEMBL7406980 | 0.71 | GPR17 (0.60) | GPR17HDAC8MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | claimed |
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |