Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.76 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.76 |
| ▸ | MMP9 | P14780 | 1/20 | 0.73 |
| ▸ | MMP8 | P22894 | 1/20 | 0.73 |
| ▸ | MMP14 | P50281 | 1/20 | 0.73 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | SNCA | P37840 | 9/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32678267 | 0.87 | MTNR1A (0.73) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL32678270 | 0.87 | MTNR1A (0.73) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL4510886 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL6028185 | 0.86 | MTNR1A (0.68) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL10310234 | 0.86 | MTNR1A (0.68) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL892461 | 0.85 | MMP9 (0.79) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL892597 | 0.85 | MMP9 (0.79) | MTNR1AMTNR1BMMP9MMP8MMP14 | |
| SCHEMBL29679229 | 0.85 | SPR (0.76) | MTNR1AMTNR1BNOTUMTSHRLMNA | |
| SCHEMBL13645692 | 0.85 | SPR (0.76) | MTNR1AMTNR1BNOTUMTSHRLMNA | |
| SCHEMBL28872536 | 0.84 | MTNR1A (0.77) | MTNR1AMTNR1BMMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | claimed |
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |