Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | USP2 | O75604 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | CASP1 | P29466 | 5/20 | 0.60 |
| ▸ | CASP7 | P55210 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557230 | 0.77 | KMT2A (0.57) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL14303302 | 0.75 | KMT2A (0.67) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL14146535 | 0.75 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL17914323 | 0.74 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL29440640 | 0.74 | MEN1 (0.73) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL394375 | 0.74 | MEN1 (0.73) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL903151 | 0.73 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL12153732 | 0.73 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL21905456 | 0.73 | MEN1 (0.55) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL30056369 | 0.73 | KMT2A (0.82) | KMT2AMEN1ALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283855-B1 | STABLE NEAR-INFRARED (NIR) MARKER DYES BASED ON BENZOPYRYLIUM-POLYMETHINES | DYOMICS GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6750346-B2 | CHROMENES AS TERMINAL END GROUPS | CARL ZEISS JENA GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20020115862-A1 | Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines | DYOMICS GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115862-A1 | Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines | CYBA, MKI67, CYP3A5 | KMT2A 3682/4885MEN1 3871/4885ALDH1A1 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.