Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167849 | 0.88 | TRPV6 (0.46) | CSF1RSLC6A2SLC6A4SLC6A3TRPV6 | |
| SCHEMBL16475192 | 0.84 | PDGFRB (0.47) | PDE1CSLC6A2SLC6A4SLC6A3TRPV6 | |
| SCHEMBL16475195 | 0.84 | PDGFRB (0.44) | PDE1CSLC6A2SLC6A4SLC6A3TRPV6 | |
| SCHEMBL15741748 | 0.83 | PDGFRB (0.40) | CSF1RNTRK1NTRK2PDE1APDE1B | |
| SCHEMBL5182802 | 0.83 | KDM4E (0.50) | PDE1CSLC6A2SLC6A4SLC6A3TRPV6 | |
| SCHEMBL628293 | 0.80 | PDE10A (0.41) | CSF1RNTRK1NTRK2SLC6A2SLC6A4 | |
| SCHEMBL4882863 | 0.80 | HTR2C (0.47) | CSF1RNTRK1NTRK2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL23130915 | 0.79 | HTR2C (0.49) | CSF1RNTRK1NTRK2 | |
| SCHEMBL2634492 | 0.79 | ESR2 (0.46) | PDE1CPIK3CASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2082609 | 0.78 | CHRNB2 (0.41) | SLC6A2SLC6A4SLC6A3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592421-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |