Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | CTSL | P07711 | 11/20 | 0.45 |
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CTSS | P25774 | 8/20 | 0.43 |
| ▸ | CTSV | O60911 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265583 | 0.91 | CTSK (0.44) | CTSBCTSLCTSKCTSS | |
| SCHEMBL6265266 | 0.90 | CTSK (0.57) | CTSBCTSLCTSKCTSSCTSV | |
| SCHEMBL6269260 | 0.84 | CTSK (0.56) | CTSBCTSLCTSKCTSS | |
| SCHEMBL5528992 | 0.83 | CTSK (0.58) | CTSBCTSLCTSKCTSSCTSV | |
| SCHEMBL6273683 | 0.81 | CTSK (0.45) | CTSBCTSLCTSKCTSSCTSV | |
| SCHEMBL6271589 | 0.81 | CTSK (0.44) | CTSBCTSLCTSKCTSS | |
| SCHEMBL6268827 | 0.80 | CTSK (0.44) | CTSBCTSLCTSKCTSSCTSV | |
| SCHEMBL6269410 | 0.79 | CTSK (0.45) | CTSBCTSLCTSKCTSS | |
| SCHEMBL6272591 | 0.79 | JAK2 (0.54) | CTSBCTSLCTSKCTSSSMN1; SMN2 | |
| SCHEMBL6272481 | 0.78 | CTSL (0.44) | CTSBCTSLCTSKCTSSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097103-A2 | DIABETES AND METABOLIC SYNDROME THERAPY UTILIZING CATHEPSIN B INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | claimed |