Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405335 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| Tetradecylthioacetic Acid SCHEMBL7524926 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL4814083 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL4649866 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| Tetradecylthioacetic Acid SCHEMBL207756 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL3638014 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL939761 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL10491282 | 0.77 | HSD17B10 (0.63) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL1405316 | 0.77 | HSD17B10 (1.00) | THRBHSD17B10GMNNTP53POLB | |
| SCHEMBL24362145 | 0.74 | THRB (0.57) | THRBHSD17B10GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| EP-1587508-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | Genfit (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004069241-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | GENFIT (FR) | 2004-08-19 | — | — | WO | disclosed |