Tetradecylthioacetic Acid

Tetradecylthioacetic Acid

SCHEMBL207756

CCCCCCCCCCCCCCSCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 1.00
GMNN O75496 1/20 1.00
TP53 P04637 1/20 1.00
POLB P06746 1/20 1.00
MAPT P10636 1/20 1.00
THRB P10828 1/20 1.00
CYP2C9 P11712 1/20 1.00
BLM P54132 1/20 1.00
CES2 O00748 3/20 0.69
CES1 P23141 5/20 0.60
FAAH O00519 4/20 0.60
PLA2G6 O60733 1/20 0.60
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405322 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1405362 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL3638014 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4814083 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1405316 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1405566 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL939761 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4354732 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
SCHEMBL4649866 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT
Tetradecylthioacetic Acid SCHEMBL7524926 1.00 HSD17B10 (1.00) HSD17B10GMNNTP53POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1095 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108482-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS INC (US) 2026-04-23 US claimed
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF T OMEGA AS (NO) 2025-11-13 US claimed
CN-113939288-B Modulators of MAS-related G protein receptor X4 and related products and methods 伊赛恩特制药公司 2025-04-25 CN claimed
EP-4522141-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF T Omega AS (NO) 2025-03-19 EP claimed
CN-119522096-A Combinations and compositions comprising niacin or derivatives thereof and fatty acids or derivatives thereof T欧米伽股份有限公司 2025-02-25 CN claimed
EP-4483376-A1 MEASUREMENT, DIAGNOSIS, TREATMENT AND MANAGEMENT OF METABOLIC SYNDROME García Sada, Fernando (MX) 2025-01-01 EP claimed
CN-118922890-A Measurement, diagnosis, treatment and management of metabolic syndrome 费尔南多·加西亚·萨达 2024-11-08 CN claimed
US-20240300907-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS INCYTE CORPORATION 2024-09-12 US claimed
US-11840521-B2 Modulators of Mas-related G-protein receptor X4 and related products and methods ESCIENT PHARMACEUTICALS, INC. (US) 2023-12-12 US claimed
WO-2023219511-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF 1/1T OMEGA AS (NO) 2023-11-16 WO claimed
EP-1232750-A1 Non-beta-oxidizable fatty acid analogues and their use for reduction of growth of cancer cells Berge, Rolf (NO) 2002-08-21 EP claimed
WO-2002043728-A1 FATTY ACID ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISORDERS THIA MEDICA AS (NO) 2002-06-06 WO claimed
WO-2002026218-A2 FATTY ACID ANALOGUES FOR THE TREATMENT OF PROLIFERATIVE SKIN DISORDERS THIA MEDICA AS (NO) 2002-04-04 WO claimed
EP-1180013-A1 LOCAL DRUG DELIVERY BIOCOMPATIBLES LTD. (GB) 2002-02-20 EP claimed
WO-2002003983-A1 FATTY ACID ANALOGUES FOR THE TREATMENT OF CANCER THIA MEDICA AS (NO) 2002-01-17 WO claimed
WO-2001001957-A1 LOCAL DRUG DELIVERY BIOCOMPATIBLES LIMITED (GB) 2001-01-11 WO claimed
US-6046237-A ADMINISTERING TO A MAMMAL AN EFFECTIVE AMOUNT OF NON-BETA-OXIDIZABLE FATTY ACID CONTAINING SELENIUM ATOM IN HYDROCARBON CHAIN FOR THE TREATMENT OF HYPERLIPIDEMIA AND ANTHEROGENIC CONDITIONS BERGE ROLF (NO) 2000-04-04 US claimed
WO-1999058120-A1 USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS BERGE ROLF (NO) 1999-11-18 WO claimed
EP-0840604-A1 NON-BETA-OXIDIZABLE FATTY ACID ANALOGUES, THEIR USES AS THERAPEUTIC ACTIVE MEDICAMENTS, AND PREPARATION THEREOF Berge, Rolf (NO) 1998-05-13 EP claimed
WO-1997003663-A1 NON-β-OXIDIZABLE FATTY ACID ANALOGUES, THEIR USES AS THERAPEUTIC ACTIVE MEDICAMENTS, AND PREPARATION THEREOF BERGE ROLF (NO) 1997-02-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840521-B2 Modulators of Mas-related G-protein receptor X4 and related products and methods MRGPRX4, MRGPRX1, MRGPRX2 HSD17B10 3465/4885GMNN 3697/4885TP53 4046/4885
US-20260108482-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS MRGPRX4, MRGPRX1, MRGPRX2 HSD17B10 1518/4885GMNN 4546/4885TP53 4536/4885
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF HADHA, HAGH, HADHB HSD17B10 414/4885GMNN 3835/4885TP53 1853/4885
US-20240300907-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS MRGPRX4, MRGPRX1, MRGPRX2 HSD17B10 3465/4885GMNN 3697/4885TP53 4046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.