Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222372 | 0.84 | KCNA5 (0.61) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL6259858 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL1492018 | 0.80 | KCNA5 (0.64) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL13743071 | 0.78 | — | — | |
| SCHEMBL8609056 | 0.77 | — | — | |
| SCHEMBL28167088 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL5324455 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL31518625 | 0.76 | KMT2A (0.50) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL30585369 | 0.75 | — | — | |
| SCHEMBL894866 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030709-A1 | NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE | LG LIFE SCIENCES LTD. (KR) | 2005-04-07 | — | — | WO | claimed |